Mar 8 2019
Dr. Best S A et al recently report their finding on NSCLC and KEAP1/NRF2 and PI3K Pathways[1]. It is well known that non-small cell lung cancer is the most common type of lung cancer, with a lower survival rate in most cancer.Adenocarcinoma (ADC) is the major histological subtype of lung cancer and the KEAP1/NRF2 pathway […]
Mar 8 2019
Recently Dr. Mainardi S, et al. found SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer. Research published at Nature Medicine on May 28, 2018. Lung cancer is the most common cause of cancer death worldwide, about 1.6 million deaths every year. Non-small cell lung cancer (NSCLC) is the primary type of lung cancer […]
Mar 8 2019
Recently, Dr. Takeshi Tanoue et al report relationship between CD8 T-cells and anti-cancer immunity. This paper was published on Nature volume 565, pages600–605 (2019) Dysbiosis of commensal microbiota can contribute to cancer onset, progression and therapy response through effects on anti-tumor immunity1-4.The currently studies have now advanced our understanding of local microbiota immunomodulation and gaveustheinsight into the potential of […]
Dec 17 2018
The 2018 Annual Scientific Symposium of MSCO was successfuly held on September 29, 2018 at Mandarin Oriental Hotel, Macau. Invited speaker including Dr. Tongyu Li from Sun Yat-sen University Cancer Center, Dr, Ding Yu and Dr. Huijing Wu from Hubei Cancer Center, Dr. Yizhun Zhu, Prof. Elaine,Leung from MUST, Dr. Xingxiang Pu from Hunan Cancer […]
May 17 2018
Dr. Elaine Lai Han Leunget al reported that Combined use of PI3K and MEK inhibitors synergistically inhibits lung cancer with EGFR and KRAS mutations EGFR and KRAS mutations are the two most common driver mutations in non-small cell lung cancer (NSCLC). Molecular target-based therapy using small molecules such as Gefitinib has been used for inhibiting EGFR with good […]
Apr 11 2019
Elaine’s group discovered a cardiac glycoside restrains EGFR-related and EGFR-independent NSCLC cell proliferation with distinct treatment mechanism
Non-small cell lung cancer (NSCLC) is the predominant histological type of lung cancer and is characterized by the highest mortality and incidence rates among these types of malignancies (1, 2). Traditional Chinese medicine (TCM) has been applied for centuries in China (3, 4). Cardiac glycosides, a class of natural products, have been identified as a […]
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By Yabing • News, Research • 0